Wound Care Research Library | SerenaGroup Publications

Cellular, acellular, and matrix-like products (CAMPs) for soft-tissue reconstruction in acute surgical and traumatic wounds

Co-chairs: Kapp, D.L. & Serena, T. Author panel: Chaffin, A.E., Desvigne, M., Kirby, J., Suski, M.D., & Tettel...

2025 JWC Consensus or guideline

Evaluation of human placental-based cellular, acellular and matrix-like products (CAMPs) in the management of nonhealing diabetic foot ulcers

Serena, T., Tramelli, B., King, E., Shi, D., Breisinger, K., Neil, M., Frania, S., Iosue, H., Namen, W., Patel...

2025 IJTR Abstract

Evaluating several cellular, acellular, and matrix-like products (CAMPs) and standard of care in the management of non-healing pressure ulcers using matched controls

Serena, T., Tramelli, B., King, E., & Chashnikova, E.

2025 IJTR Abstract

A multicenter, prospective randomized controlled modified dual platform trial evaluating several CAMPs and standard of care vs. standard of care alone in the management of nonhealing diabetic foot ulcers and venous leg ulcers

Serena, T., Tramelli, B., & King, E.

2025 IJTR Abstract

Evaluation of cellular, acellular, and matrix-like products in the management of nonhealing venous leg ulcers

Serena, T.E., Tramelli, B., Dunn, M., King, E., & Shi, D.

2025 IJTR Abstract

Evaluation of multiple cellular, acellular, and matrix-like products (CAMPs) and standard of care vs. standard of care alone in the treatment of nonhealing diabetic foot ulcers

Serena, T., Tramelli, B., Wilkins, S., & Tunyiswa, Z.

2025 IJTR Abstract

Evaluation of cellular, acellular, and matrix-like products (CAMPs) in the management of nonhealing diabetic foot ulcers

Serena, T.E., Tramelli, B., King, E., Shi, D., Dunn, M., Mehta, M., Simon, D., & Pavelescu, R.A.

2025 IJTR Abstract

Evaluation of intact fish skin grafts plus standard care in the treatment of venous leg ulcers: an abstract

Serena, T.E., Tramelli, B., Booker, B., King, E., Shi, D., & Lantis, J.C.

2025 IJTR Abstract

Evaluation of intact fish skin grafts plus standard of care in the treatment of venous leg ulcers: research article

Serena, T.E., Tramelli, B., Booker, B., King, E., Shi, D., & Lantis, J.C.

2025 IJTR Research article

Standardised Reporting Outcomes for trials investigating Surgical WOund Complications (ROSWOC) Protocol for the development of a core outcomes set

Sandy-Hodgetts, K., Russo, P.L., Smith, G., Rochon, M., Wainwright, T.W., Totty, J., Serena, T., McLean, K., A...

2025 Impact Surgery Trial protocol

Flourescence Imaging in Surgical Wound Management - A consensus-based approach

Chair: Serena, T.E. Authors: Kapp, D., Davenport, T., Tettlebach, W., Bohn, G., Lantis, J.C., Suski, M., Low, ...

2025 IJTR Consensus or guideline

A multicentre, prospective, randomized controlled modified platform trial evaluating PURION processed lyophilized human amnion/chorion membrane and standard of care versus standard of care alone in the treatment of non-healing diabetic foot ulcers

Serena, T.E., Tramelli, B., King, E., & Maloumi, S.

2025 IJTR Trial protocol

Evaluation of lyophilized human amnion chorion membrane (LHACM) in the management of nonhealing diabetic foot ulcers

Serena, T.E., Tramelli, B., Bonafide, B., & Tunyiswa, Z.

2025 IJTR Abstract

Evaluation of dual layer amnion patch on the healing rate of chronic diabetic foot ulcers

Serena, T., Tramelli, B., Tunyiswa, Z., Schrecengost, N., & Alexandre, C.

2025 IJTR Abstract

Efficacy of placental derived allografts and standard of care in the treatment of nonhealing diabetic foot ulcers using matched controls

Serena, T., Tramelli, B., & King, E.

2025 IJTR Abstract

Evaluation of amnion chorion amnion placental allograft in the management of nonhealing diabetic foot ulcers and venous leg ulcers

Serena, T., McGurk, S., Tramelli, B., King, E., Shi, D., Bohn, G., & Ohse, H.

2025 IJTR Abstract

Full thickness placental membrane allograft for diabetic foot ulcers

Serena, T., Chashnikova, E., Tramelli, B., King, E., Shi, D., Bohn, G., & Ohse, H.

2025 IJTR Abstract

Evaluation of acellular human dermis graft on the healing rate of chronic diabetic foot ulcers

Serena, T., Tramelli, B., & Tunyiswa, Z.

2025 IJTR Abstract

Evaluating the efficacy of placental-derived allograft in managing non-healing pressure ulcers

Serena, T., McGurk, S., King, E., Tramelli, B., Shi, D., & Breisinger, K.

2025 IJTR Research article

Evaluation of single layer amniotic membrane in the management of nonhealing diabetic foot ulcers

Serena, T.E., Tramelli, B., King, E., Shi, D., Bohn, G., & Breisinger, R.

2025 IJTR Research article

Clinical trials for cellular, acellular and matrix-like products (CAMPs): an evidence consensus

Serena, T.E. (Chair), Andersen, C., Bohn, G., Cosentino, G., Davis, M., Desvigne, M., Kaur, A., Low, M., Oropa...

2025 IJTR Consensus or guideline

A Diagnostic-Driven Prospective Clinical Study Evaluating the Combination of an Antibiofilm Agent and Negative Pressure Wound Therapy

Serena, T.E., King, E., Serena, L., Breisinger, K., Al-Jalodi, O., & Myntti, M.F.

2024 Diagnostics Research article

A double-blind trial comparing an antimicrobial combination to standard care in hard-to-heal wounds

Khan, M., King, E., Breisinger, K., Serena, L., & Serena, T.E.

2024 JWC Research article

Percentage area reduction at week 4 as a prognostic indicator of complete healing in patients treated with standard of care: a post hoc analysis

Serena, T., Yaakov, S., Yaakov, R., King, E., & Driver, V.R.

2024 JWC Research article

Skin Substitutes for the Treatment of Hard-to-Heal Wounds

Expert panel. Mulder, G. (Chair), Lavery, L.A., Marston, W.A., Nair, H.K.R., Oropallo, A., Wahab, N., Romanell...

2024 Wounds International Consensus or guideline

Suggested minimal evidence for CAMP coverage

Serena, T. (sole author)

2023 JWC Commentary or editorial

Skin Pigmentation Impacts the Clinical Diagnosis of Wound Infection: Imaging of Bacterial Burden to Overcome Diagnostic Limitations

Johnson, J., Johnson, A.R. Jr., Andersen, C.A., Kelso, M.R., Oropallo, A.R., & Serena, T.E.

2023 J Racial Ethn Health Disparities Research article

A Clinical Trial Design for Evaluating Topical Antimicrobials in Chronic Wounds: The BLEU Trial

Serena, T., King, E., Boyer, T., & Harrell, K.

2023 Life Trial protocol

Proceedings of the Leaders in Wound Healing Conference: 2023

SerenaGroup Research Foundation (conference proceedings, no individual byline)

2023 JWC Conference proceedings

Use of Topical Oxygen Therapy in Wound Healing

Frykberg, R. (Panel chair), Andersen, C., Chadwick, P., Haser, P., Janssen, S., Lee, A., Niezgoda, J., Serena,...

2023 JWC Consensus or guideline

Fluorescence Image Guided Use of an Antibiofilm Agent in the Treatment of Recalcitrant Pilonidal Ulcers: A Case Review

Garcia, L.T., Georgiades, A., Serena, L.M., & Serena, T.

2023 Annals Case Rep Rev Case report or series

Point-of-care fluorescence imaging reveals extent of bacterial load in diabetic foot ulcers

Armstrong, D.G., Edmonds, M.E., & Serena, T.E.

2023 Int Wound J Research article

Point-of-care fluorescence imaging to optimise wound bed preparation prior to cellular and/or tissue-based product(CTP) application

Serena, T.E.

2023 Int Wound J Commentary or editorial

Use of fluorescence imaging to optimize location of tissue sampling in hard-to-heal wounds

See PDF author block - Serena listed

2023 Frontiers CIMB Research article

Reliance on Clinical Signs and Symptoms Assessment Leads to Misuse of Antimicrobials: Post hoc Analysis of 350 Chronic Wounds

Serena, T.E., Gould, L., Ousey, K., & Kirsner, R.S.

2022 Adv Wound Care Research article

Uncovering the high prevalence of bacterial burden in surgical site wounds with point-of-care fluorescence imaging

Sandy-Hodgetts, K., Andersen, C.A., Al-Jalodi, O., Serena, L., Teimouri, C., & Serena, T.E.

2022 Int Wound J Research article

Optimizing Prevention of Surgical Wound Complications: Detection, Diagnosis, Surveillance and Prediction

ISWCAP expert panel. Sandy-Hodgetts, K. (Chair), Alves, P., Conway, B., Djohan, R., Idensohn, P., McIsaac, C.,...

2022 Wounds International Consensus or guideline

A Multicenter, Randomized, Controlled, Clinical Trial Evaluating Dehydrated Human Amniotic Membrane in the Treatment of Venous Leg Ulcers

Serena, T.E., Orgill, D.P., Armstrong, D.G., Galiano, R.D., Glat, P.M., Carter, M.J., Kaufman, J.P., Li, W.W.,...

2022 Plast Reconstr Surg Research article

Evaluation of the combination of a biofilm-disrupting agent and negative pressure wound therapy: a case series

Serena, T.E., Jalodi, O., Serena, L., Patel, K., & Myntti, M.

2021 JWC Research article

Guidelines for the use of topical oxygen therapy in the treatment of hard to heal wounds based on a delphi consensus.

Serena, T., Andersen, C., Cole, W., Garoufalis, M., & Frykberg, R.

2021 Wound Central Consensus or guideline

Molecular Biomarkers of Oxygen Therapy in Patients with Diabetic Foot Ulcers

Oropallo, A.R., Serena, T.E., Armstrong, D.G., & Niederauer, M.Q.

2021 Biomolecules Commentary or editorial

Topical oxygen therapy in the treatment of diabetic foot ulcers: a multicentre, open, randomised controlled clinical trial

Serena, T.E., Bullock, N.M., Cole, W., Lantis, J., Li, L., Sabo, M., Wahab, N., & Price, P.

2021 JWC Research article

Are Semi-Quantitative Clinical Cultures Inadequate? Comparison to Quantitative Analysis of 1053 Bacterial Isolates from 350 Wounds

Serena, T.E., Bowler, P.G., Schultz, G.S., D'souza, A., & Rennie, M.Y.

2021 Diagnostics Research article

Enhancing Patient Centricity and Advancing Innovation in Clinical Research with Virtual Randomized ClinicalTrials (vRCTs)

Yaakov, R.A., Guler, O., Mayhugh, T., & Serena, T.E.

2021 Diagnostics Commentary or editorial

Proceedings of the Leaders in Wound Healing Conference: 2021

Serena, T. (sole author)

2021 Wound Central Commentary or editorial

Proposal for a New Pressure Ulcer (Pressure Injury) Classification Based on Depth, Infection and Perfusion

Manzotti-Rodriguez, A.C., Lozano-Platonoff, A., Serena, T.E., Bryant, R., & Contreras-Ruiz, J.

2021 Wound Central Research article

Diagnostic Accuracy of Point-of-Care Fluorescence Imaging for the Detection of Bacterial Burden in Wounds: Results from the 350-Patient Fluorescence Imaging Assessment and Guidance Trial

Le, L., Baer, M., Briggs, P., Bullock, N., Cole, W., DiMarco, D., Hamil, R., Harrell, K., Kasper, M., Li, W., ...

2021 Adv Wound Care Research article

Guidelines for Point-of-Care Fluorescence Imaging for Detection of Wound Bacterial Burden Based on Delphi Consensus

Oropallo, A.R., Andersen, C., Abdo, R., Hurlow, J., Kelso, M., Melin, M., & Serena, T.E.

2021 Diagnostics Consensus or guideline

A prospective, randomized, controlled, crossover study comparing three multilayered foam dressings for the management of chronic wounds

Alvarez, O.M., Granick, M.S., Reyzelman, A., & Serena, T.

2021 J Comp Eff Res Research article

Comparing near infrared spectroscopy and transcutaneous oxygen measurement in hard-to-heal wounds: a pilot study

Serena, T.E., Yaakov, R., Serena, L., Mayhugh, T., & Harrell, K.

2020 JWC Research article

Hyperbaric oxygen therapy in preventing mechanical ventilation in COVID-19 patients: a retrospective case series

Thibodeaux, K., Speyrer, M., Yaakov, R., Serena, T.E., & Raza, A.

2020 JWC Research article

The Early Identification and Prevention of Surgical Wound Complications

ISWCAP expert panel. Sandy-Hodgetts, K. (President), Ousey, K. (Vice President), Conway, B., Djohan, R., Nair,...

2020 Wounds International Consensus or guideline

Optics are the Astronomy of Wound Healing

Serena, T.E. (sole author)

2020 Wound Central Commentary or editorial

Incorporating Point-of-Care Bacterial Fluorescence into a Wound Clinic Antimicrobial Stewardship Program

Serena, T.E. (sole author)

2020 Diagnostics Trial protocol

A randomized controlled clinical trial of a hypothermically stored amniotic membrane for use in diabetic foot ulcers

Serena, T.E., Yaakov, R., Moore, S., Cole, W., Coe, S., Snyder, R., Patel, K., Doner, B., Kasper, M.A., Hamil,...

2020 J Comp Eff Res Research article

A New Term: The Point of Pathogenicity

Serena, T.E. (sole author)

2019 Adv Skin Wound Care Commentary or editorial

Real-time bacterial fluorescence imaging accurately identifies wounds with moderate-to-heavy bacterial burden

Serena, T.E., Harrell, K., Serena, L., & Yaakov, R.A.

2019 JWC Research article

Skin Graft Donor Site Management in the Treatment of Burn and Hard-to-Heal Wounds

Romanelli, M. (Chair), Serena, T. (Chair), Kimble, R., Han, S-K., Kim, J.T., Cruz, J.J.V., Xin, C., Chong, S.J...

2018 WUWHS Consensus or guideline

Fresh hypothermically stored amniotic allograft in the treatment of chronic nonhealing ulcers: a prospective case series

Sabo, M., Moore, S., Yaakov, R., Doner, B., Patel, K., & Serena, T.E.

2018 CWCMR Case report or series

Changes in the extracellular matrix surrounding human chronic wounds revealed by 2-photon imaging

Sutcliffe, J.E.S., Thrasivoulou, C., Serena, T.E., Madden, L., Richards, T., Phillips, A.R.J., & Becker, D.L.

2017 Int Wound J Research article

Preventing, minimizing, and managing pain in patients with chronic wounds: challenges and solutions

Serena, T.E., Yaakov, R.A., Aslam, S., & Aslam, R.S.

2016 CWCMR Review

Outcomes of Radiation Injuries Using Hyperbaric Oxygen Therapy: An Observational Cohort Study

Niezgoda, J.A., Serena, T.E., & Carter, M.J.

2016 Adv Skin Wound Care Research article

Novel Multivalent Wound-Healing Ointment Provides Bioburden Control and Moisture Management: A Retrospective Registry Data Analysis

Serena, T., Connell, H., McConnell, S., Patel, K., Doner, B., Sabo, M., Miller, M., Serena, L., Le, L.T., Gold...

2016 Adv Skin Wound Care Case report or series

Defining a New Diagnostic Assessment Parameter for Wound Care: Elevated Protease Activity (EPA), an Indicator of Non-healing, for Targeted Protease-modulating Treatment

Serena, T.E., Cullen, B.M., Bayliff, S.W., Gibson, M.C., Carter, M.J., Chen, L., Yaakov, R.A., Samies, J., Sab...

2016 Wound Repair Regen Research article

A prospective, randomised, controlled, multicentre clinical trial examining healing rates, safety and cost to closure of an acellular reticular allogenic human dermis versus standard of care in the treatment of chronic diabetic foot ulcers

Zelen, C.M., Orgill, D.P., Serena, T., Galiano, R., Carter, M.J., DiDomenico, L.A., Keller, J., Kaufman, J., &...

2016 Int Wound J Research article

Aseptically Processed Placental Membrane Improves Healing of Diabetic Foot Ulcerations: Prospective, Randomized Clinical Trial

DiDomenico, L.A., Orgill, D.P., Galiano, R.D., Serena, T.E., Carter, M.J., Kaufman, J.P., Young, N.J., & Zelen...

2016 PRS Global Open Research article

A multicenter, randomized, controlled clinical trial evaluating the use of dehydrated human amnion/chorion membrane allografts and multilayer compression therapy vs. multilayer compression therapy alone in the treatment of venous leg ulcers

Serena, T.E., Carter, M.J., Le, L.T., Sabo, M.J., DiMarco, D.T., & the EpiFix VLU Study Group

2014 Wound Repair Regen Research article

A prospective, randomised comparative study of weekly versus biweekly application of dehydrated human amnion/chorion membrane allograft in the management of diabetic foot ulcers

Zelen, C.M., Serena, T.E., & Snyder, R.J.

2014 Int Wound J Research article

A prospective, randomised, controlled, multi-centre comparative effectiveness study of healing using dehydrated human amnion/chorion membrane allograft, bioengineered skin substitute or standard of care for treatment of chronic lower extremity diabetic ulcers

Zelen, C.M., Gould, L., Serena, T.E., Carter, M.J., Keller, J., & Li, W.W.

2014 Int Wound J Research article

Consensus principles for wound care research obtained using a Delphi process

Serena, T., Bates-Jensen, B., Carter, M.J., Cordrey, R., Driver, V., Fife, C.E., Haser, P.B., Krasner, D., Nus...

2012 Wound Repair Regen Research article

SensiLase Studycast System: A Platform for Critical Limb Diagnostics and Electronic Referral Program

Serena, T. (sole author)

2012 Adv Wound Care Research article

The wound care evidence library