IJTR · 2025

Efficacy of placental derived allografts and standard of care in the treatment of nonhealing diabetic foot ulcers using matched controls

Serena, T., Tramelli, B., & King, E.

International Journal of Tissue Repair (IJTR), randomized controlled trial, matched controls

In brief

This abstract describes the RENEW trial, a multicenter, prospective randomized controlled modified platform study designed to evaluate multiple placental-derived allografts used alongside standard care in patients with non-healing diabetic foot ulcers. The study uses matched controls and aims to generate evidence on the effectiveness of these products to help guide their use in clinical practice. No trial results are reported in this abstract.

SerenaGroup was contracted by Sequence LifeScience to run this trial.

Plain-language summary by SerenaGroup. See the full text for complete methods and results.

Abstract

Efficacy of placental derived allografts and standard of care in the treatment of nonhealing diabetic foot ulcers using matched controls: a randomized controlled trial Thomas Serena,1 MD | Brianna Tramelli ,2 | Emily King,3 MS SerenaGroup, Inc., Cambridge, MA 02142, USA

Keywords

diabetic foot ulcerchronic woundsplacental derived allografttissue regenerationclinical trial design

Efficacy of placental derived allografts and standard of care in the treatment of nonhealing diabetic foot ulcers using matched controls

In brief

Abstract

Keywords

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