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Publications library Commentary or editorial

Adv Skin Wound Care · 2019

A New Term: The Point of Pathogenicity

Serena, T.E. (sole author)

Advances in Skin & Wound Care, December 2019, p535 (Letters)

In brief

In this letter, the author argues that the term "critical colonization" is a misnomer for the stage at which bacteria in a chronic wound move from colonization to invading tissue, and proposes the term "point of pathogenicity" instead. He defines it as the point at which bacteria begin producing proteases that break down host tissue, which can precede clinical signs and symptoms of infection, citing his own trial data on bacterial protease activity. He suggests that testing for bacterial protease activity may allow earlier detection of infection at this stage.

Written by Dr. Thomas Serena, SerenaGroup's founder.

Plain-language summary by SerenaGroup. See the full text for complete methods and results.

No abstract is published for this item. Use the full text link for the complete document.