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Publications library Consensus or guideline

Wounds International · 2024

Skin Substitutes for the Treatment of Hard-to-Heal Wounds

Expert panel. Mulder, G. (Chair), Lavery, L.A., Marston, W.A., Nair, H.K.R., Oropallo, A., Wahab, N., Romanelli, M., & Serena, T.E.

Wounds International, international consensus document

In brief

This international consensus document, developed by an expert panel that met in June 2024, aims to clarify terminology and classification for skin substitutes, summarize available evidence, and provide practical guidance for their selection and application in hard-to-heal wounds. The panel distinguishes between biological dressings and biological matrices, discusses their use across wound types including diabetic foot ulcers, venous leg ulcers, and pressure injuries, and emphasizes comprehensive patient and wound assessment, structured wound bed preparation using frameworks such as TIMERS, and following manufacturer instructions. The document also recommends reassessing the patient and treatment plan when a wound has not improved after approximately four weeks and highlights the need for stronger clinical evidence, particularly for wound types beyond diabetic foot ulcers.

Co-authored by Dr. Thomas Serena, SerenaGroup's founder, as a member of the expert panel.

Plain-language summary by SerenaGroup. See the full text for complete methods and results.

No abstract is published for this item. Use the full text link for the complete document.