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Adv Skin Wound Care · 2016

Outcomes of Radiation Injuries Using Hyperbaric Oxygen Therapy: An Observational Cohort Study

Niezgoda, J.A., Serena, T.E., & Carter, M.J.

Advances in Skin & Wound Care, 2016;29:12-19

In brief

This observational study analyzed 2538 patients with late radiation injuries who received hyperbaric oxygen therapy, using data from the American College of Hyperbaric Medicine's Radionecrosis Research Registry entered at 108 US treatment facilities. The share of patients whose symptoms improved or resolved ranged from 76.7% for laryngeal radionecrosis to 92.6% for radiation proctitis, depending on injury type. The study had no comparison group, and the authors state that randomized controlled trials are still needed to establish hyperbaric oxygen as a standard of care for these injuries.

Co-authored by Dr. Thomas Serena, SerenaGroup's founder.

Plain-language summary by SerenaGroup. See the full text for complete methods and results.

Abstract

LIMITATIONS: Limited data were available on patient comorbidities and symptom severity. CONCLUSIONS: Outcomes from a large patient registry of radiation-induced injuries support the continued therapeutic use of HBOT for radiation injuries.