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Publications library Research article

JWC · 2015

Dehydrated human amnion/chorion membrane treatment of venous leg ulcers: correlation between 4-week and 24-week outcomes

See PDF author block - Serena listed

Journal of Wound Care, 2015 (MA Healthcare)

In brief

This retrospective follow-up of a multicenter randomized trial in venous leg ulcers asked whether reaching at least 40% wound area reduction after 4 weeks of treatment predicts complete healing within 24 weeks. Among 44 evaluable patients, 16/20 (80%) of those with at least 40% reduction at 4 weeks healed within 24 weeks versus 8/24 (33.3%) of those with less reduction (p=0.0027). Among patients who healed, mean time to healing was 46 days in the ≥40% reduction group versus 103.6 days in the <40% group (p=0.0023). Week 4 status correctly matched 24-week healing status in 32 of 44 patients (72.7%), supporting its potential use as an intermediate outcome.

Led by SerenaGroup researchers, with Dr. Thomas Serena as first author.

Plain-language summary by SerenaGroup. See the full text for complete methods and results.

No abstract is published for this item. Use the full text link for the complete document.