Publications library Research article
Frontiers CIMB · 2023
See PDF author block - Serena listed
Frontiers in Cellular and Infection Microbiology, published 12 January 2023
This post hoc analysis of the 350-wound FLAAG trial examined 78 hard-to-heal wounds that were biopsied at two sites: the wound center, as in standard care, and a site chosen using point-of-care fluorescence imaging. Fluorescence-guided biopsies found high bacterial loads more often than center biopsies (sensitivity 98.7% vs 87.2%, p=0.0059) and detected more bacterial species per sample (3.03 vs 2.2, p<0.001), including more species the CDC lists as antibiotic resistance threats. Wounds that received a second biopsy were larger than those biopsied once, and the authors conclude that fluorescence imaging can help select a more representative sampling site, particularly in large wounds.
The SerenaGroup Research Foundation conducted the FLAAG trial behind this analysis, sponsored by MolecuLight.
Plain-language summary by SerenaGroup. See the full text for complete methods and results.
No abstract is published for this item. Use the full text link for the complete document.
