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Publications library Consensus or guideline

CWCMR · 2026

Expert Roundtable Recommendations on Wound-Bed Optimization in Difficult-to-Heal Wounds: Clinical Positioning of ON101 From a U.S. Multidisciplinary Roundtable

Serena, T.E. (chair), Kapp, D.L. (chair), Lantis, J.C., Desvigne, M.N., Pfendler, L., Suski, M., Bohn, G., Tunyiswa, Z., Low, M., Chaffin, A.E., & Liden, B.A.

Journal of Chronic Wound Care Management and Research (CWCMR)

In brief

This paper reports recommendations from a structured expert roundtable of 11 panelists, held in April 2026, on the role of ON101, a topical wound-bed optimization matrix, in difficult-to-heal wounds. The panel concluded that ON101 may be considered as an adjunct to comprehensive wound care, particularly for difficult-to-heal diabetic foot ulcers, where the evidence is strongest, and that use in other wound types, optimal timing, and dosing require prospective study. The authors state the recommendations are expert opinion rather than formal clinical practice guidelines, and the roundtable and manuscript were funded by Oneness Biotech, the manufacturer of ON101.

Co-chaired by Dr. Thomas Serena, SerenaGroup's founder, with SerenaGroup researchers on the panel.

Plain-language summary by SerenaGroup. See the full text for complete methods and results.

No abstract is published for this item. Use the full text link for the complete document.

Keywords

ON101expert roundtablewound-bed optimizationdifficult-to-heal woundsdiabetic foot ulcerconsensus