Uncovering the high prevalence of bacterial burden in surgical site wounds with point-of-care fluorescence imaging

Abstract

Detection of bacterial burden within or near surgical wounds is critical to reducing the occurrence of surgical site infection (SSI). A distinct lack of reli- 2 Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia 3 able methods to identify postoperative bioburden has forced reliance on clinical signs and symptoms of infection (CSS). As a result, infection management has been reactive, rather than proactive. Fluorescence imaging of bacterial Wound Care Clinic, Madigan Army Medical Center, Joint Base LewisMcChord, Renton, Washington, USA burden (FL) is positioned to potentially flip that paradigm. This post hoc analysis evaluated 58 imaged and biopsied surgical site wounds from the multi- 4 centre fluorescence imaging assessment and guidance clinical trial. Diagnostic SerenaGroup Research Foundation, Cambridge, Massachusetts, USA 5 Beaver Valley Foot Clinic, Pittsburgh, Pennsylvania, USA

Keywords

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